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The 72-Kda Component Of Signal Recognition Particle Is Cleaved During Apoptosis

JOURNAL OF BIOLOGICAL CHEMISTRY, no. 52 (1998): 35362-35370

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Proteins cleaved by apoptotic caspases are commonly recognized by autoantibodies found in the serum of patients with rheumatic disease. We report that the 72-kDa signal recognition particle (SRP) protein, a rare target of autoantibodies found in the serum of patients with dermatomyositis and systemic lupus erythematosus, is rapidly cleave...更多

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