Cerebrovascular Risk Factors and Depression in Older Primary Care Patients: Testing a Vascular Brain Disease Model of Depression
The American Journal of Geriatric Psychiatry(1999)
摘要
The authors examined whether cerebrovascular risk factors (CVRFs) are associated with depressive diagnoses and symptoms in 303 primary-care patients age greater than or equal to 60 years, as would be consistent with a small-vessel brain disease model of later-life depression. CVRFs were not significantly independently associated with major, minor, or subsyndromal depression, late-onset major depression, or overall depressive symptom severity. These data did not support the notion that a small-vessel brain disease model of depression might apply to the majority of older persons with depressive symptoms and syndromes in primary-care settings. Future work should include longitudinal study with larger sample sizes.
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关键词
risk factors
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