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Calmodulin And Protein Kinase C Increase Ca2+-Stimulated Secretion By Modulating Membrane-Attached Exocytic Machinery
JOURNAL OF BIOLOGICAL CHEMISTRY, no. 37 (1999): 26469-26476
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The molecular mechanisms underlying the Ca2+ regulation of hormone and neurotransmitter release are largely unknown. Using a reconstituted [H-3]norepinephrine release assay in permeabilized PC12 cells, we found that essential proteins that support the triggering stage of Ca2+-stimulated exocytosis are enriched in an EGTA extract of brain ...更多
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