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Autoproteolysis in nucleoporin biogenesis.

Proceedings of the National Academy of Sciences of the United States of America, no. 20 (1999): 11370-11375

Cited by: 92|Views2
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Abstract

We have molecularly characterized a proteolytic cleavage in conserved nuclear pore complex proteins. This cleavage, previously demonstrated to be essential for the biogenesis of two nuclear pore complex proteins in mammals (Nup98 and Nup96) and yeast (Nup145-N and Nup145-C), occurs between Phe and Ser residues within a highly conserved do...More

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