Homogeneous pd-catalyzed enantioselective decarboxylative protonation.

General homogeneous conditions for the palladium-catalyzed synthesis of carbonyl compounds with tertiary carbon stereocenters at the alpha-position are reported. The highly reactive catalyst tolerates a variety of substrate substitution and-functionality, and generates enantioenriched cyclic ketones from racemic allyl beta-ketoester starting materials.