Measurements of the acidification kinetics of single SynaptopHluorin vesicles.
Biophysical Journal, no. 7 (2011): 1580-1589
Uptake of neurotransmitters into synaptic vesicles is driven by the proton gradient established across the vesicle membrane. The acidification of synaptic vesicles, therefore, is a crucial component of vesicle function. Here we present measurements of acidification rate constants from isolated, single synaptic vesicles. Vesicles were puri...More
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