Changes in expression levels of immune cells and inflammatory cytokines in pre-eclampsia patients before and after delivery

Cuihua Shen, Ying Song, Wei Fan, Xiaojuan Guo, Jia Li,Renbin Zhao

Journal of Reproductive Immunology(2023)

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摘要
•By analyze the expression levels of immune cells and cytokines secreted by preeclampsia patients before and after delivery, it is found that PE patients may reduce CD4 + cells and CD8 + cells, and down-regulate the level of cytokines (especially TNF-β) secreted by Th1 cells to reduce the maternal rejection of embryos, thereby reducing the risk of premature delivery, which is a protective adaptive compensation mechanism in favor of embryos.
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关键词
Preeclampsia,Cytokines,Immune cells,CD4+cell,CD8+cell,TNF-β
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