Clinical drugs that interact with St. John's wort and implication in drug development

Current pharmaceutical design, Volume 14, Issue 17, 2008, Pages 1723-1742.

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St. John's wort (Hypericum perforatum, SJW) is one of the most commonly used herbal antidepressants for the treatment of minor to moderate depression. A major safety concern about SJW is its ability to alter the pharmacokinetics and/or clinical response of a variety of clinically important drugs that have distinctive chemical structure, m...更多

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