Sulfonyl-morpholino-pyrimidines: SAR and development of a novel class of selective mTOR kinase inhibitor.
Bioorganic & Medicinal Chemistry Letters(2012)
摘要
The identification of mTOR kinase inhibitor hits from HTS screening and their development into leads such as 32 is described
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关键词
Kinase,Enzyme,Inhibitor,mTOR
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