Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA.

Neoplasia(2013)

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摘要
BACKGROUND: Percentage of free-to-total prostate-specific antigen (%fPSA) is an independent predictor of risk for prostate cancer among men with modestly elevated level of total PSA (tPSA) in blood. Physiological and pathological factors have been shown to influence the %fPSA value and diagnostic accuracy.
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关键词
genome wide association study,genotype,case control studies,transcription factors
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