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Using intracranial EEG, we have identified the location of a neuronal population within the inferior temporal gyrus with greater activation to visual symbols denoting numerals compared with morphologically, semantically, or phonologically similar symbols

A Brain Area For Visual Numerals

JOURNAL OF NEUROSCIENCE, no. 16 (2013): 6709-6715

被引用101|浏览45
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摘要

Is there a distinct area within the human visual system that has a preferential response to numerals, as there is for faces, words, or scenes? We addressed this question using intracranial electrophysiological recordings and observed a significantly higher response in the high-frequency broadband range (high gamma, 65-150 Hz) to visually ...更多

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简介
  • A current model of numerical cognition predicts that, within the ventral stream of the human visual system, there is likely to be a region that responds more to visual numerals than to other stimuli (Dehaene, 2011).
  • This hypothesized region for visual numerals should be anatomically consistent across subjects and should respond more to numerals than morphologically, semantically, or phonologically similar stimuli.
重点内容
  • A current model of numerical cognition predicts that, within the ventral stream of the human visual system, there is likely to be a region that responds more to visual numerals than to other stimuli (Dehaene, 2011)
  • Is there a distinct area within the human visual system that has a preferential response to numerals, as there is for faces, words, or scenes? We addressed this question using intracranial electrophysiological recordings and observed a significantly higher response in the high-frequency broadband range to visually presented numerals, compared with morphologically similar or semantically and phonologically similar stimuli
  • Because visual numerals are culturally dependent symbols that are only learned through education, our novel finding of anatomically localized preferential response to such symbols provides a new example of acquired category-specific responses in the human visual system
  • Using intracranial EEG, we have identified the location of a neuronal population within the inferior temporal gyrus with greater activation to visual symbols denoting numerals compared with morphologically, semantically, or phonologically similar symbols
  • The novelty of our finding is both in identifying the precise anatomical location of neurons with a preferential response to visual numerals as well as in highlighting that these neurons are imbedded within a larger pool of neurons that respond nonpreferentially to visual symbols that have lines, angles, and curves. Further study of this cortical area is essential to underence of the fMRI eclipse zone in the inferior temporal gyrus region within the healthy stand developmental and cultural factors that explain how a control subjects
  • The inferior temporal gyrus region with a preferential response to certain population of neurons within a pool of nonpreferential numerals identified in our subjects falls surprisingly close to, or neurons gains preferential responses to visual symbols, such as within, the fMRI eclipse zone
方法
  • Subjects This study involved seven (3 female and 4 male) right-handed individuals (Table 1) with electrode coverage over the inferior temporal and occipital regions.
  • Electrode coverage Female College 69 R Male High school
结果
  • A large mantle of the VOT region encompassing its key anatomical regions of interest were covered, specific electrode positioning differed between subjects.
  • In Experiment 1 (Fig. 1), the authors tested the hypothesis that there is an area within the inferior temporal region that has a significantly larger response to numerals compared with morphologically similar stimuli, such as letters or false fonts.
  • In Experiment 2 (Fig. 1), the authors tested the hypothesis that the preferential response to numerals remains larger even if compared with words with similar semantic and/or phonetic content (e.g., “1” compared with “one” or “won”; “6” compared with “six” or “sex,” etc.).
  • A repeated-measures ANOVA with a Greenhouse-Geisser correction determined that mean response times were not significantly different among conditions in Experiment 1 (F(1.009,6.052) ϭ 1.332, p ϭ 0.293) or Experiment 2 (F(1.050,6.298) ϭ 2.380, p ϭ 0.172)
结论
  • Using intracranial EEG, the authors have identified the location of a neuronal population within the ITG with greater activation to visual symbols denoting numerals compared with morphologically, semantically, or phonologically similar symbols.
  • The novelty of the finding is both in identifying the precise anatomical location of neurons with a preferential response to visual numerals as well as in highlighting that these neurons are imbedded within a larger pool of neurons that respond nonpreferentially to visual symbols that have lines, angles, and curves
  • Further study of this cortical area is essential to underence of the fMRI eclipse zone in the ITG region within the healthy stand developmental and cultural factors that explain how a control subjects.
  • To determine the exact nature of numeral processing in the ITG, future studies need to explore the structural and functional connections between the ITG and its adjacent VOT structures, earlier visual cortex, and parietofrontal areas involved in language and memory
表格
  • Table1: Subject demographics Subjects Age (years) Gender
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基金
  • This work was supported in part by the National Institutes of Health Grant 1R01 NS0783961 to J.P., Stanford
引用论文
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