Lack of MERS coronavirus neutralizing antibodies in humans, eastern province, Saudi Arabia.

Stefanie Gierer,Heike Hofmann-Winkler,Waleed H Albuali,Stephanie Bertram,Abdullah M Al-Rubaish,Abdullah A Yousef,Awatif N Al-Nafaie,Amein K Al-Ali,Obeid E Obeid,Khaled R Alkharsah,Stefan Pöhlmann

EMERGING INFECTIOUS DISEASES（2013）

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摘要

We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS-CoV infections in humans are infrequent in this province.

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mers coronavirus,mers-cov,middle east respiratory syndrome coronavirus,saudi arabia,coronavirus,neutralizing antibodies,plasma,pseudotyping,respiratory infections,seroprevalence,serum,spike,viruses,young adult

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