Coordination of Rho family GTPase activities to orchestrate cytoskeleton responses during cell wound repair.

•Rho, Cdc42, and Rac1 are required to control actin and myosin dynamics upon wounding•Segregation of Rho family GTPase arrays is necessary for crosstalk among the GTPases•Cytoskeleton feedback is needed to maintain and translocate Rho family GTPase arrays•Diaphanous, Rok, and Pkn are downstream effectors of Rho1 GTPase in cell wound repair