Nanofilaments on glioblastoma exosomes revealed by peak force microscopy.
JOURNAL OF THE ROYAL SOCIETY INTERFACE(2015)
摘要
Exosomes are sub-100 nm extracellular vesicles secreted by normal and cancer cells. We present a high-resolution structure of previously unidentified nanofilaments on glioblastoma-derived exosomes, using nanoscale peak force imaging. These stiff, adhesive, trypsin-and RNAse-resistant surface nanofilaments add a new dimension to the current structural knowledge of exosome-mediated intercellular communication.
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关键词
nanoparticles,glioblastoma exosomes,nanofilaments,intercellular communication,nanotechnology
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