Protein Kinase C Mediates Memory Consolidation of Taste Avoidance Conditioning in Lymnaea Stagnalis.

•The critical role of PKC activation for memory enhancement was examined.•Twenty paired CS–US presentations resulted in STM and LTM.•Pre-exposure to PKC activator formed STM with 5 paired CS–US presentations.•Pre-incubation with PKC activator facilitated STM into LTM.•Pre-incubation with PKC inhibitor failed to form both STM and LTM.