Rv1027c-Rv1028c encode functional KdpDE two--component system in Mycobacterium tuberculosis.

Biochemical and Biophysical Research Communications（2014）

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摘要

•Rv1027c–Rv1028c encode functional KdpDE two component system in M. tuberculosis.•His642 and Asp52 are identified as phosphorylation sites.•Phosphorylation sensitive interaction of the KdpDE protein by SPR is reported.•Co-transcription of KdpD and KdpE genes observed under K+ ion limitation conditions.

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关键词

Two component system,Mycobacterium tuberculosis,Sensor kinase,Response regulator,KdpDE

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