Acute Lymphocytic Cholangitis and Liver Failure in an Amur Tiger (panthera Tigris Altaica).
Journal of zoo and wildlife medicine(2014)
Abstract
An adult male Amur tiger (Panthera tigris altaica) with confirmed inflammatory bowel disease developed acute severe icterus, bilirubinuria, bilirubinemia, and elevated bile acids after a diet change. Liver biopsies showed moderate lymphoplasmacytic cholangiohepatitis (lymphocytic cholangitis). The tiger developed neurologic signs including ataxia, tremors, and seizures, as well as epistaxis. Therapy consisted of antibiotics, a steroid anti-inflammatory, vitamins, pro-coagulants, and liver-supportive medicines. The tiger improved from acute liver failure within 3 wk, while the epistaxis began at 3.5 wk and did not resolve until 10.5 wk. The long-term maintenance plan consists of oral prednisolone, metronidazole, ursodiol, and an all muscle-meat beef diet.
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Key words
Amur tiger,bilirubinuria,cholangiohepatitis,liver failure,lymphocytic cholangitis,Panthera tigris altaica
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