Curcumol suppresses RANKL-induced osteoclast formation by attenuating the JNK signaling pathway.

Mingxiang Yu,Xianying Chen,Chaoyang Lv,Xilu Yi,Yao Zhang,Mengjuan Xue,Shunmei He,Guoying Zhu,Hongfu Wang

Biochemical and Biophysical Research Communications（2014）

引用 22|浏览7

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摘要

•Curcumol suppresses osteoclasts differentiation in vitro.•Curcumol impairs JNK/AP-1 signaling pathway.•Curcumol may be used for treating osteoclast related diseases.

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关键词

Curcumol,Antiresorptive agent,Osteoclast,RANKL,JNK

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