Involvement of nitric oxide (NO) signaling pathway in the antidepressant action of the total flavonoids extracted from Xiaobuxin-Tang.

Li-Ming Zhang,Heng-Lin Wang,Nan Zhao,Hong-Xia Chen,Yun-Feng Li,You-Zhi Zhang

Neuroscience Letters（2014）

引用 15|浏览35

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摘要

•XBXT-2 presented antidepressant-like effects in the mouse forced swim test (FST).•The antidepressant effect of XBXT-2 was reversed by pretreatment with l-arginine.•7-Nitroindazole potentiated the antidepressant effect of XBXT-2.

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关键词

ANOVA,eNOS,FST,iNOS,NMDA,nNOS,NO,NOS,SSRIs,TCM,XBXT,XBXT-2

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