Persistence of serogroup C antibody responses following quadrivalent meningococcal conjugate vaccination in United States military personnel.

Manisha Patel,Sandra Romero-Steiner,Michael P Broderick,Cynthia G Thomas,Brian D Plikaytis,Daniel S Schmidt,Scott E Johnson,Andrea S Milton,George M Carlone,Thomas A Clark,Nancy E Messonnier,Amanda C Cohn,Dennis J Faix

Vaccine（2014）

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摘要

•We evaluated duration of protection of meningococcal conjugate vaccines.•Only 54% of meningococcal conjugate vaccinees were protected at 3 years.•A booster dose is needed to sustain protection in high risk groups.

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ACIP,CDC,DMSS,DoD,DoDSR,ELISA,GMC,GMT,LLQ,MenACYW,MenACYWD,MenC,MPSV4,NHRC,rSBA,VE

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