An analysis of FDA-approved drugs for infectious disease: antibacterial agents.

Michael S Kinch,Eric Patridge,Mark Plummer,Denton Hoyer

Drug Discovery Today（2014）

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摘要

•New approval for infectious disease NMEs have plummeted across many pathogen types.•The attrition of antibiotics from resistance/obsolescence exceeds new approvals.•Industry has largely dismantled its capabilities for developing new antibiotics.

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