Equine herpesvirus type 1 pUL56 modulates innate responses of airway epithelial cells.

Virology(2014)

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摘要
Recently, the product of equine herpesvirus type 1 (EHV-1) ORF1, a homolog to HSV-1 pUL56, was shown to modulate MHC-I expression and innate immunity. Here, we investigated modulation of respiratory epithelial immunity by EHV-1 pUL56 and compared responses to those of PBMCs, which are important target cells that allow cell-associated EHV-1 viremia.
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关键词
Equine herpesvirus-1,Respiratory epithelium,pUL56,Innate immunity
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