Protective Effects of Adiponectin on Uncoupling of Glomerular VEGF–NO Axis in Early Streptozotocin-Induced Type 2 Diabetic Rats

Ningning Hou,Na Huang,Fang Han,Jiangang Zhao,Xue Liu,Xiaodong Sun

International urology and nephrology（2014）

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摘要

To determine whether adiponectin could reduce microalbuminuria and provide renal protective effects by improving endothelial dysfunction and uncoupling of the glomerular vascular endothelial growth factor (VEGF)–nitric oxide (NO) axis in streptozotocin-induced type 2 diabetic rats.

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关键词

Adiponectin,Microalbuminuria,Vascular endothelial growth factor,Nitric oxide,Diabetic nephropathy

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