Structural studies of virus-antibody immune complexes (poliovirus type I): Characterization of the epitopes in 3D.

Ludovic Bannwarth,Yves Girerd-Chambaz,Ana A Arteni,Jean-Michel Guigner,Jacques Lemains,Frédéric Ronzon,Catherine Manin,Catherine Vénien-Bryan

Molecular Immunology（2015）

引用 12|浏览6

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摘要

•TEM analysis of poliovirus–Fab and poliovirus–Mab complexes.•Description of the epitopes recognized by anti-type 1 poliovirus Fabs 234, 236, 237, 423 and 73-5-5.•The antigenic site for Mab73-5-5 is located at the bottom of the canyon.

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关键词

Polio vaccine,Poliovirus type 1,Antigenic site,Cryo-electron microscopy,Image analysis,Monoclonal antibody

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