Functional and genomic context in pathway analysis of GWAS data.
Trends in Genetics(2014)
摘要
•Gene set analyses (GSAs) will extend the knowledge gained from GWAS.•There is no consensus about the best way to perform GSA.•The wide variety of analysis methods makes it difficult to compare GSA results.•Steps must be taken to improve the interpretability and comparability of GSA.
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关键词
gene set analysis,GWAS,polygenic effects,complex traits
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