A Synthesis of 6-Deoxy-6-fluorosucrose Suitable for Pet Applications

Xuefeng Gao,Vikram Gaddam,Michael Harmata

Carbohydrate research（2014）

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摘要

A new route to 6-deoxy-6-fluorosucrose has been developed. The process proceeds in 8 linear steps in 25% overall yield from sucrose. The steps incorporating fluorine and subsequent deprotection are quite rapid, making the procedure useful in the context of 18F-labeling for PET applications.

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关键词

Fluorination,Fluorosucrose,Fluorosugar,Kryptofix [2.2.2]

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