Novel extracellular matrix biomarkers as predictors of adverse outcome in chronic heart failure: association between biglycan and response to statin therapy in the CORONA trial.

Thor Ueland,Pål Aukrust,Ståle H Nymo,John Kjekshus,John J V McMurray,John Wikstrand,Dirk Block,Christian Zaugg,Lars Gullestad

Journal of Cardiac Failure（2015）

引用 14|浏览30

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摘要

•Biglycan and mimecan added no predictive information on adverse outcome in HF.•An interaction between biglycan and statin treatment was observed.•HF patients with low biglycan levels had a beneficial effect of statin treatment on outcomes.

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关键词

Heart failure,adverse outcome,extra cellular matrix,biglycan,mimecan

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