Synthesis and characterisation of glucose-functional glycopolymers and gold nanoparticles: study of their potential interactions with ovine red blood cells.
Carbohydrate Research(2015)
Abstract
•This research studies how glucose-rich nanostructures interact with erythrocytes.•Glycopolymers were obtained by RAFT polymerisation of a glucose-methacrylamide.•Gold nanoparticles were decorated with glucose on their corona.•Several assays revealed no evidence of polymer binding to the cells.•The results suggest glucose rich polymers are compatible with erythrocytes.
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Key words
Glycobiology,Nanoparticle,Biocompatibility,Glycopolymer,Blood
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