Zyxin antagonizes the FERM protein expanded to couple F-actin and Yorkie-dependent organ growth.

Pedro Gaspar,Maxine V Holder,Birgit L Aerne,Florence Janody,Nicolas Tapon

Current Biology（2015）

引用 65|浏览9

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摘要

•Zyx antagonizes Ex to control growth, eye differentiation, and F-actin•Membrane targeting of Zyx promotes tissue growth and Yki activity•Zyx modulates Yki target gene expression and the interaction of Sd with Yki•The Ena-binding region of Zyx is required to antagonize Ex function

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