Multipurpose prevention technologies: the future of HIV and STI protection.

•HIV, other sexually transmitted infections (STIs), and unintended pregnancy are global health crises.•Multipurpose prevention technologies (MPTs) are being developed to protect against HIV, other STIs, and, in some cases, unintended pregnancy within a single product.•MPTs need to be carefully conceived in the context of the entire breath of regulatory complexities and risks that will potentially apply.