Secondary pharmacology data to assess potential off-target activity of new drugs: a regulatory perspective
NATURE REVIEWS DRUG DISCOVERY(2015)
摘要
Secondary pharmacology studies evaluate compounds for pharmacodynamic activity against a broad range of targets that are related to or distinct from the intended therapeutic target. This is a cost-effective approach used by many pharmaceutical companies as a safety screen early in drug development, as highlighted in a recent article (Reducing… Download references
更多查看译文
关键词
Drug regulation, Drug safety
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要