A rare truncating BRCA2 variant and genetic susceptibility to upper aerodigestive tract cancer
Journal of the National Cancer Institute, Volume 107, Issue 5, 2015.
Deleterious BRCA2 genetic variants markedly increase risk of developing breast cancer. A rare truncating BRCA2 genetic variant, rs11571833 (K3326X), has been associated with a 2.5-fold risk of lung squamous cell carcinoma but only a modest 26% increase in breast cancer risk. We analyzed the association between BRCA2 SNP rs11571833 and upp...More
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