Activating transcription factor 4 promotes angiogenesis of breast cancer through enhanced macrophage recruitment

BIOMED RESEARCH INTERNATIONAL, pp. 974615-974615, 2015.

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Abstract:

Angiogenesis plays an important role in the progression of tumor. Besides being regulated by tumor cells per se, tumor angiogenesis is also influenced by stromal cells in tumor microenvironment (TME), for example, tumor associated macrophages (TAMs). Activating transcription factor 4 (ATF4), a member of the ATF/CREB family, has been repor...More

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