Assessment of Apical Expression of Alpha-2 Integrin, Heat Shock Protein, and Proinflammatory and Immunoregulatory Cytokines in Response to Endodontic Infection

Journal of Endodontics, pp. 1085-1090, 2015.

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Abstract:

•We show proinflammatory mediators decrease after root canal cleaning procedures 1 week after chemomechanical debridement.•We examine changes in the messenger RNA expression of the integrins SSP1/OPN and FAK as well as Hsp47/SERPINH1 and ITGA2 in samples from the periapical area.•The regulatory cytokine IL-10 was higher in samples from th...More

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