Inhibitory Effect of 5|[bgr]|-Pregnane-3|[agr]|,20|[bgr]|-Diol on Transcriptional Activity and Enzyme Activity of Human Bilirubin UDP-Glucuronosyltransferase

Pediatric Research, Volume 70, Issue 5, 2011, Pages 453-457.

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Abstract:

Prolonged unconjugated hyperbilirubinemia in infants associated with breast milk feeding is a common pediatric problem known as breast milk jaundice (BMJ). A polymorphic mutation (G71R) of bilirubin UDP-glucuronosyltransferase (UGT1A1) is a known cause of BMJ on the infantile side, but the responsible components of breast milk are not cur...More

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