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Mechanisms of action of BCL6 during germinal center B cell development

Science China. Life sciences, no. 12 (2015): 1226-1232

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Abstract The transcriptional repressor B cell lymphoma 6 (BCL6) controls a large transcriptional network that is required for the formation and maintenance of germinal centers (GC). GC B cells represent the normal counterpart of most human B-cell lymphomas, which are often characterized by deregulated BCL6 expression or BCL6-mediated path...More

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