Repeated-dose liver micronucleus test of 4,4'-methylenedianiline using young adult rats.

Hisakazu Sanada,Naomi Koyama,Yumi Wako,Kazufumi Kawasako,Shuichi Hamada

Mutation Research/Genetic Toxicology and Environmental Mutagenesis（2015）

引用 5|浏览14

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摘要

•We evaluated the genotoxicity of MDA by repeated-dose liver micronucleus test.•MDA dose-dependently induced micronuclei in hepatocytes.•An obvious increase in micronuclei was not observed in bone-marrow cells.

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关键词

Liver micronucleus tests,4,4′-methylenedianiline,General toxicity test

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