WS3.2 The effect of ivacaftor treatment on lung ventilation defects, as measured by hyperpolarized helium-3 MRI, on patients with cystic fibrosis and a G551D-CFTR mutation

WS3.1 The effect of ivacaftor on the rate of lung function decline in CF patients with a G551D-CFTR mutation G.S. Sawicki1, E. McKone2, D.J. Pasta3, J. Wagener4, C. Johnson4, M.W. Konstan5. 1Boston Children’s Hospital, Boston, United States; 2St. Vincent’s University Hospital, Dublin, Ireland; 3ICON Late Phase and Outcomes Research, San Francisco, United States; 4Vertex Pharmaceuticals Incorporated, Boston, United States; 5Case Western Reserve University School of Medicine Rainbow Babies and Children’s Hospital, Cleveland, United States