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Pneumococcal Polysaccharide Vaccination in Rheumatoid Arthritis Patients Receiving Tacrolimus

Kiyoshi Migita,Yukihiro Akeda,Manabu Akazawa,Shigeto Tohma,Fuminori Hirano,Haruko Ideguchi,Ryutaro Matsumura,Eiichi Suematsu,Tomoya Miyamura,Shunsuke Mori,Takahiro Fukui,Yasumori Izumi,Nozomi Iwanaga,Hiroshi Tsutani,Kouichirou Saisyo,Takao Yamanaka,Shiro Ohshima,Takao Sugiyama,Yojiro Kawabe,Masao Katayama,Yasuo Suenaga,Akira Okamoto, Hisaji Ohshima,Yasumasa Okada,Kenji Ichikawa,Shigeru Yoshizawa,Kenji Kawakami,Toshihiro Matsui,Hiroshi Furukawa,Kazunori Oishi

Arthritis research & therapy（2015）

引用 28|浏览19
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摘要
In rheumatoid arthritis (RA) patients receiving immunosuppressive treatments, vaccination against Streptococcus pneumoniae is recommended. The objective of the study was to evaluate the effects of tacrolimus (TAC) on immune response following administration of a 23-valent pneumococcal polysaccharide vaccine (PPSV23) in patients with established RA.
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关键词
Rheumatoid Arthritis Patient,Abatacept,Pneumococcal Vaccination,Opsonization Index,Positive Antibody Response
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