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Epigallocatechin-3-gallate regulates cell growth, cell cycle and phosphorylated nuclear factor-|[kappa]|B in human dermal fibroblasts

Acta Pharmacologica Sinica, no. 5 (2011): 637-646

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Abstract

Aim: To investigate the effects of (-) epigallocatechin-3-gallate (EGCG), the main polyphenol in green tea, on cell growth, cell cycle and phosphorylated nuclear factor-kappa B (pNF-kappa B) expression in neonatal human dermal fibroblasts (nHDFs). Methods: The proliferation and cell-cycle of nHDFs were determined using WST-8 cell growth a...More

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