Gender Difference In Antidepressant-Related Sexual Dysfunction In Patients With Major Depressive Disorder (Mdd)
European Psychiatry(2012)
摘要
Introduction It is known that Sexual Dysfunction (SD) is higher in patient with depression than in the general population. Though antidepressant seems to worsen the situation, there are also indications that the gender may play a role on it. Objective Evaluate the gender effect of sexual function among unmedicated MDD, MDD receiving antidepressant, and healthy controls. Methods The sample was formed by male and female Taiwanese outpatients in three age and sex matched groups, with sixty nine participants per group: unmedicated MDD, MDD receiving antidepressant, and healthy controls. The diagnoses of depressions were performed according DSM-IV and Taiwanese Depression Questionnaire. SD was evaluated with the Chinese version of the Changes in Sexual Functioning Questionnaire. Finally, the data was analyzed using SPSS software v17. Mixed designed ANOVA was used. Results There are significant differences between males and females CSFQ results (sex main effect F = 82.44, p Conclusions SD is different between genders in each of the groups. Antidepressant seems to increase SD in man, while improves sexual satisfaction/function among depressive woman. We speculate that psychological improvement after treatment may have different impact between genders on sexual satisfaction.
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