Characterization of Rabbit Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are multipotent stem cells that can be isolated from bone marrow and adipose tissue. They are characterized by their adherence to plastic and ability to differentiate into adipocytes, osteocytes and chondrocytes. The objective of this project was to thoroughly characterize rabbit MSCs isolated from adipose tissue. Few markers have been identified for characterizing rabbit MSCs. This is due, in part, to the availability of rabbit antibodies that cross react with the rabbit cells. Protocols for differentiating rabbit MSCs into mesodermal cell types have also yet to be optimized.