Oxidative Damage and Reproductive Toxicity of Organic Extracts of Jilin City Reach of the Second Songhua River on Male Rats

Objective: To evaluate the potential hazards of organic pollutants in Jilin City Reach of the second Songhua River. Methods: organic pollutants of water was concentrated and tested by vivo experiments on rats. Results : Testis organ coefficient decreased and sperm deformity rate increased with the increase of OE dose in each water samples from low water period and high water period. A significant decrease of SOD activity and a increase of MDA content of testis was observed at 50mL/kg group of midstream, 25 mL/kg, 50 mL/kg group of downstream from high water period. Furthermore, reproductive toxicity of organic extracts in high water period was higher that in low water period in Jilin City Reach of the second Songhua River. Conclusion : Organic pollutants of water in Jilin City Reach of the second Songhua River have potential reproductive toxicity effects.