Human pulmonary artery endothelial cells in the model of mucopolysaccharidosis VI present a prohypertensive phenotype
Molecular Genetics and Metabolism Reports（2015）
摘要
Our data suggest that MPS VI endothelium presents a prohypertensive phenotype due to the reduction of endothelium's proliferation ability and expression of vasorelaxing factors.
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关键词
Pulmonary hypertension,Endothelial cells,Endothelium,Proliferation,Apoptosis,Endothelial nitric oxide synthase,Natriuretic peptide type C,Vascular endothelial growth factor
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