Characterization of Intermediate Conductance K + Channels in Submandibular Gland Acinar Cells
The Korean Journal of Physiology and Pharmacology(2002)
摘要
to 0.55±0.33 (n=5, Pģ0.05) at the maximum channel activity. The degree of BK channel activation induced by the same concentration of CCh was lower than that of IK channels; Po value was 0.011±0.003 and 0.027±0.005 in control and during CCh stimulation (n=3), respectively. The result suggests that IK channels exist in salivary acinar cells and its channel activity is regulated by muscaricinic and ǰ - adrenergic agonist. We conclude that IK channels also play a putative role in secretion as well as the BK channels in rat submandibular gland acinar cells.
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