GW26-e3875 Diabetes Blunt the Compensatory Enhancement of SUMOylation Intensity of Sarcoplasmic Reticulum Calcium-transporting ATPase After Myocardial Infarction

Jing Yao,Tianchang Li,Shao Xinghui,Zhengming Xu,Mengyue Yu,Siyong Teng,Yongjian Wu

Journal of the American College of Cardiology（2015）

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摘要

Diabetes is an independent risk factor of heart failure and mortality after myocardial infarction(MI). The activity and expression of Sarcoplasmic Reticulum Calcium-transporting ATPase (SERCA2a) decrease in diabetes, leading to diastolic and systolic dysfunction of myocardium. It was recently

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