Resveratrol triggers ER stress-mediated apoptosis by disrupting N-linked glycosylation of proteins in ovarian cancer cells

•Resveratrol induced ER stress-mediated apoptosis via inhibition of protein glycosylation in a cancer cell-specific manner.•Resveratrol disrupted protein glycosylation through suppression of hexosamine biosynthetic pathway.•Akt/ GSK3β involved in the resveratrol-induced interruption of protein glycosylation and ER stress-mediated apoptosis.