Synthesis and acetylcholinesterase inhibitory activities of tabersonine derivatives

Phytochemistry Letters(2015)

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摘要
•10 Novel tabersonine derivatives were synthesized using tabersonine as lead compound.•The AChE inhibitory activities of tabersonine derivatives were evaluated.•Compound (7) showed the highest AChE inhibitory activity with IC50 was 5.32μM.
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关键词
Voacanga seeds,Tabersonine derivatives,AChE inhibitory activities
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