A facile one-pot synthesis of novel 2,5-disubstituted-1,3,4-oxadiazoles under conventional and microwave conditions and evaluation of their in vitro antimicrobial activities

ARABIAN JOURNAL OF CHEMISTRY, pp. S2853-S2861, 2017.

Cited by: 2|Views5

Abstract:

A rapid and efficient solvent-free synthesis of 2,5-disubstituted-1,3,4-oxadiazoles (3a-l) from fatty acid hydrazides (1a-f) under microwave irradiation is described. The structural elucidation of these compounds is based on their spectral data (IR, H-1 NMR, C-13 NMR and MS). All the newly synthesized compounds have been screened for thei...More

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