OL-043 HBV DNA Change Between HBeAg Positive and Negative Patients with Chronic Hepatitis B

6: Hepatitis B S29 Methods: Among 33 naïve chronic hepatitis B patients, the serum level Changes of sCD26 and sCD30 before, 1 and 3 months after the start of therapy with IFNa were evaluated using sandwich enzyme-linked immonosorbant assay.The success Rate of treatment with IFNa was also obtained in these patients.Result: sCD26 serum level changes before the start of therapy till one month (P = 0.001) and three months (P < 0.001) after the start of therapy were related to success rate of therapy.sCD30 serum level changes were not related to treatment success.Conclusion: Using changes of serum level of sCD26 might be useful in predicting the outcome of therapy in naïve chronic hepatitis B patients undergoing treatment with IFNa.More studies with longer follow up time in this topic are recommended.